A TaqI RFLP detected by the probe VK45C6 [D16S131] at 16p13.11

TaqI RFLP at D21S137.

Chromosomal Localization: The 3 polymorphic bands were mapped to chromosome 22 using a somatic cell hybrid panel. The 2.1 kb constant band mapped to chromosome lq whereas all other constant bands mapped to chromosome 20. Whereas the active gene for hTOPl is located on chromosome 20ql 1.2—13.1, two pseudogenes are on chromosomes Iq23—24 and 22qll.2-13.1 (2). The sequences of hTOPl and the two ps...

RFLP detected at the 8924 locus by a thyroglobulin cDNA probe

SOURCE : 1660 bp corresponding to two contiguous Pst I fragments from human thyroglobulin gene cDNA cloned in pBR 322 (ref. I). This cDNA probe is located Ca 100 Kb 3 1 from PCHT 16/3.2-8.0 probe that reveals polymorphic fragments previously described by Baas et al. (ref.II). POLYMORPHISM : PvuII identifies a single two allele polymorphism Al : 13.2 Kb A2 : 4.4 Kb Mst II identifies a single two...

A new TaqI allele detected by the CRI-R227 (D4S101) probe in Pima Indians.

No abstract available]

A third TaqI allele is detected by the probe pTD3-21 (D15S10) in southern African chromosomes.

Primer Sequences: 5' CCT CCA CAT GGA CTC ACC TG 3' (CA strand); 5' AAG GGG AGG GAA TCA GGT GT 3' (TG strand). Polymorphism: Heterozygosity was estimated at 74% by analysis of 92 chromosomes from unrelated individuals. Allele Bl B2 B3 B4 B5 B6 B7 B8 B9 B10 bp 194 192 190 188 186 184 182 180 178 176 Frequency 0.01 0.05 0.10 0.05 0.06 0.21 0.43 ND 0.01 0.08 Chromosomal Localisation: Fluorescence i...

A TaqI RFLP for the human arylsulfatase A gene.